Quinoline ligands and metal complexes for diagnosis and therapy
US6277841A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 2, 2000 |
| Grant date | Aug 21, 2001 |
| Priority date | — |
| Expiry date | Mar 2, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/26
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel ligands for forming metal complexes that absorb or fluoresce in the visible or near-infrared (NIR) region of the electromagnetic spectrum, new complexes incorporating such ligands, process for preparing such complexes, and methods of imaging or therapy using such agents. More particularly, the present invention specifically pertains to novel metal complexes derived from quinoline based heterocyclic N.sub.2 O.sub.3, N.sub.3 O.sub.3, N.sub.3 O.sub.4, N.sub.3 O.sub.5 and N.sub.2 OS ligands, and are useful as general imaging, diagnostic, or therapeutic agents employing optical, nuclear medicine, or magnetic resonance procedures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.