Chemical compounds
US6277880A · kind A · utility
0Cited by
4References
15Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | May 19, 1999 |
| Grant date | Aug 21, 2001 |
| Priority date | — |
| Expiry date | May 19, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C311/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Prodrugs, of generic formula I, are disclosed for use in antibody directed enzyme prodrug therapy (ADEPT). The prodrugs are substrates for carboxypeptidase G2 (CPG2) and yield more active cytotoxic drugs than known products of CPG2 catalysed reactions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.