Kits & systems for ultrasonic imaging
US6280705A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 26, 1998 |
| Grant date | Aug 28, 2001 |
| Priority date | — |
| Expiry date | Jan 26, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/227
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A gas emulsion forming composition comprising a dry, hollow, particulate, approximately microspherical material permeated with a gas or gas mixture, which upon dissolution in aqueous liquid forms a gas emulsion comprising a plurality of bubbles surrounded by a layer of at least a first and a second surfactant, wherein the first surfactant consists essentially of a phospholipid or mixture of phospholipids having at least one acyl chain which comprises at least 10 carbon atoms, and comprising at least about 5% w/w of total surfactant, and wherein the second surfactant may or may not be a phospholipid and is more water soluble than the first surfactant; kits for preparing such microbubbles; and methods for using such microbubbles as contrast agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.