Compositions containing thrombin and microfibrillar collagen and methods for preparation and use thereof
US6280727A · kind A · utility
66Cited by
24References
42Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 9, 1999 |
| Grant date | Aug 28, 2001 |
| Priority date | — |
| Expiry date | Nov 9, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2400/04
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to thrombin-containing hemostatic compositions, their preparation and use. In particular, it relates to hemostatic compositions comprising stabilized thrombin and microfibrillar collagen in an aqueous medium. In a preferred embodiment of the present invention, the compositions are used in a kit comprising two different components, one of which is autologous patient's plasma as the source of fibrinogen, and the other of which is the thrombin-containing composition which also contains microfibrillar collagen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.