Process for preparation of hydroxyapatite coatings
US6280789A · kind A · utility
38Cited by
5References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 28, 1999 |
| Grant date | Aug 28, 2001 |
| Priority date | — |
| Expiry date | Jun 28, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC04B2111/00844
- WIPO fieldMaterials, metallurgy
- WIPO sectorChemistry
Abstract
Coatings of scarcely crystalline carbonated hydroxyapatite are deposited on metallic or ceramic substrates, by immersing the substrates in a solution containing calcium phosphate and bicarbonate ions, with a molar ratio calcium/phosphate from 0.8 to 2 and a pH from 6.8 to 8.0. Subsequently, the solution is heated to 50-80.degree. C., thus raising the pH and causing a spontaneous deposition of carbonated hydroxyapatite on the substrates. The obtained coatings are highly biocompatible, osteoconductive, bioactive and biodegradable, and can be utilized in structures used for preparing orthopaedic and dental prostheses and implants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.