Nucleic acid indexing
US6280948A · kind A · utility
52Cited by
16References
29Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 3, 1999 |
| Grant date | Aug 28, 2001 |
| Priority date | — |
| Expiry date | Sep 3, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/1065
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A restriction site indexing method for selectively amplifying any fragment generated by a Class II restriction enzyme includes adaptors specific to fragment ends containing adaptor indexing sequences complementary to fragment indexing sequences near the termini of fragments generated by Class II enzyme cleavage A method for combinatorial indexing facilitates amplification of restriction fragments whose sequence is not known. Profiling methods and other methods for characterizing polynucleotides are presented.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.