Interleukin-1 receptor accessory proteins, nucleic acids and methods
US6280955A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Dec 16, 1997 |
| Grant date | Aug 28, 2001 |
| Priority date | — |
| Expiry date | Dec 16, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/20
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides methods and compositions relating to IL-1RAcP proteins that regulate cellular signal transduction and transcriptional activation, and related nucleic acids. The polypeptides may be produced recombinantly from transformed host cells from the disclosed IL-1RAcP encoding nucleic acids purified from human cells. The invention provides isolated IL-1RAcP hybridization probes and primers capable of specifically hybridizing with the disclosed IL-1RAcP genes, IL-1RAcP-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.