Matrix-free osteogenic devices, implants and methods of use thereof
US6281195A · kind A · utility
247Cited by
6References
25Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 5, 1998 |
| Grant date | Aug 28, 2001 |
| Priority date | — |
| Expiry date | Feb 5, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods for inducing bone formation in a mammal sufficient to fill a defect defining a void, wherein osteogenic protein is provided alone or dispersed in a biocompatible non-rigid, amorphous carrier having no defined surfaces. The methods and devices provide injectable formulations for filling critical size defects, as well as for accelerating the rate and enhancing the quality of bone formation in non-critical size defects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.