19-nor steroids having a thiocarbonated chain in position 11beta, their preparation process and the intermediates of this process, and the intermediates of this process, their use as medicaments and compositions
US6281204A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 9, 1994 |
| Grant date | Aug 28, 2001 |
| Priority date | — |
| Expiry date | Jun 9, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J43/003
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula (I), wherein R.sub.17 and R'.sub.17 are such that: either R.sub.17 and R'.sub.17 together form ketone, hydrazono, oxime or methylene, or R.sub.17 is hydroxyl, hydroxymethyl or acyloxy and R'.sub.17 is hydrogen, alkyl or optionally substitued alkenyl or alkynyl; R.sub.3 is hydrogen or alkyl; R.sub.16 is hydrogen, halogen or alkyl; m is 0, 1 or 2; X, Y and Z are such that: X is methylene, arylene or arylenoxy bonded to the steroid by a carbon atom; Y is a saturated or unsaturated straight or branched aliphatic chain which is optionally interrupted by oxygen; and Z is aryl, arylalkyl or straight or branched alkyl; addition salts thereof, a preparation method therefor, medicinal uses thereof, compositions containing said compounds, and resulting novel intermediates. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.