Substituted semicarbazides and the use thereof
US6281211A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 21, 2000 |
| Grant date | Aug 28, 2001 |
| Priority date | — |
| Expiry date | Sep 21, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention is related to substituted semicarbazides represented by Formula (I) or a pharmaceutically acceptable salt or prodrug thereof, wherein: R.sub.1 and R.sub.2 are independently hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, haloalkyl, aryl, aminoalkyl, hydroxyalkyl, alkoxyalkyl or carboxyalkyl; R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are independently hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, haloalkyl, aryl, aminoalkyl, hydroxyalkyl, alkoxyalkyl or carboxyalkyl, or R.sub.3 and R.sub.4 is defined as above, and R.sub.5 and R.sub.6 together with the nitrogen atom to which they are attached form a heterocycle, including piperidine, piperazine, morpholine; A.sub.1 and A.sub.2 are independently aryl, heteroaryl, saturated or partially unsaturated carbocycle or saturated or partially unsaturated heterocycle, any of which is optionally substituted; X is one of O, S, NR.sub.7, CH.sub.2, C(O), NR.sub.7 C(O), C(O)NR.sub.7, SO, SO.sub.2 or a covalent bond; where R.sub.7 is hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, haloalkyl, aryl, aminoalkyl, hydroxyalkyl, alkoxyalkyl or carboxyalkyl; n is 0, 1, 2 or 3. m is 0, 1, 2 or 3. The invention also is directed to the use of substit…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.