Rat ob-receptors and nucleotides encoding them
US6281346A · kind A · utility
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16Claims
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Key dates
| Filing date | Feb 20, 1997 |
| Grant date | Aug 28, 2001 |
| Priority date | — |
| Expiry date | Feb 20, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/72
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The rat ob receptor gene has been isolated and cloned. Two different alleles have been identified: the wild-type, and the fa-allele which differs from the wild type by only one base pair. The base pair change, however introduces an MspI restriction site into the DNA sequence, and also results in an amino acid change. Also part of the invention are the receptors, vectors containing the nucleic acid encoding the receptors, host cells transformed with this gene, and assays which use the gene or protein and identify new ligands.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.