Means for creating a mass having structural integrity
US6284270A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 4, 1999 |
| Grant date | Sep 4, 2001 |
| Priority date | — |
| Expiry date | Aug 4, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1658
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a means for creating a mass having structural integrity, including a rapidly disintegratable tablet for administration with or without the use of water. The present invention has a wide variety of different uses and applications. One embodiment is a tablet intended for oral administration. The tablet comprises at least one active ingredient and a mixture of excipients. The excipients provide desired characteristics and physical properties and when the tablet is sintered or heated, excellent tablet binding characteristics are obtained. The tablet is intended primarily for oral administration and dissolves in the presence of water. Also disclosed is a process for the preparation of a rapidly disintegratable tablet for administration with or without the use of water. The process comprising dissolving at least one bulking agent and at least one structural agent in a suitable solvent, wherein the solvent provides high porosity upon drying; spray-drying or dispersing said dissolved mixture to obtain a bead or granulated product; dry blending at least one binding agent, and at least one active ingredient with the bead or granulated product to obtain a pref…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.