RNA export element and methods of use
US6284469A · kind A · utility
7Cited by
2References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 20, 2000 |
| Grant date | Sep 4, 2001 |
| Priority date | — |
| Expiry date | Jun 20, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2730/10122
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A cis-acting posttranscriptional regulatory element (PRE) useful for efficient RNA export of RNA is provided. The element, termed WPRE, is originally derived from woodchuck hepatitis virus. The invention also provides a method for enhancing the expression of transgenes by insertion of the WPRE nucleic acid sequences in operably linkage with the transgene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.