Nucleic acid arrays and methods of synthesis
US6284497A · kind A · utility
84Cited by
7References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 8, 1999 |
| Grant date | Sep 4, 2001 |
| Priority date | — |
| Expiry date | Apr 8, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention generally relates to high density nucleic acid arrays and methods of synthesizing nucleic acid sequences on a solid surface. Specifically, the present invention contemplates the use of stabilized nucleic acid primer sequences immobilized on solid surfaces, and circular nucleic acid sequence templates combined with the use of isothermal rolling circle amplification to thereby increase nucleic acid sequence concentrations in a sample or on an array of nucleic acid sequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.