Patent · US Expired

3-Hydroxy-3-methylglutaryl-CoA reductase polynucleotides in isoprenoid production

US6284506A · kind A · utility

45Cited by
0References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 6, 1999
Grant dateSep 4, 2001
Priority date
Expiry dateMay 6, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P23/00
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to an isolated DNA sequence encoding an enzyme in the mevalonate pathway or the pathway from isopentenyl pyrophosphate to farnesyl pyrophosphate (i.e., HMG-CoA synthase, HMG-CoA reductase, mevalonate kinase, mevalonate pyrophosphate decarboxylase, and FPP synthase). Vectors and plasmids including such DNA, are also set forth. The invention also includes host cells transformed by such DNAs, or vectors or plasmids containing such DNAs. A process for the production of isoprenoids and carotenoids using such transformed host cells is also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.