1-phenyl-4-(1-[2-aryl]cyclopropyl)methylpiperazines: dopamine receptor ligands
US6284761A · kind A · utility
10Cited by
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41Claims
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Key dates
| Filing date | Jan 6, 2000 |
| Grant date | Sep 4, 2001 |
| Priority date | — |
| Expiry date | Jan 6, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/135
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compounds of the formula: ##STR1## or pharmaceutically acceptable addition salts thereof wherein: PA1 R.sub.1, R.sub.2, R.sub.3 R.sub.4 and R.sub.5, R.sub.6, R.sub.7, and R.sub.8 represent organic and/or inorganic substituents as defined herein, PA2 which compounds are useful for the treatment and/or prevention of neuropsychological disorders including, but not limited to, schizophrenia, mania, dementia, depression, anxiety, compulsive behavior, substance abuse, Parkinson-like motor disorders and motion disorders related to the use of neuroleptic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.