Method for producing salts of cyclic amidines

US6284892A · kind A · utility

Assignee

• Degussa-Huels AG · DE

Inventors

• Dieter Most · Bruchköbel, DE
• Karlheinz Drauz · Alzenau, DE

Key dates

• Filing date: Jun 7, 2000
• Grant date: Sep 4, 2001
• Expiry date: Jun 7, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D207/22
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for the production of salts of cyclic amidines of the general formula (I) ##STR1## The processes described hitherto as prior art enable salts of the compound (I) to be produced only at low yields. As a result of protecting .omega.-amino-.alpha.-amino acids selectively at the .omega.-amino function, oxidative decarboxylation of the latter protected compounds by means of halogen derivatives, and subsequent cyclisation of the oxidatively decarboxylated substances with the addition of acid, according to the invention salts of the compound (I) are achieved in better yields.