Patent · US Expired

Proteinase K resistant surface protein of neisseria meningitidis

US6287574A · kind A · utility

8Cited by
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9Claims
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Key dates

Filing dateNov 13, 1997
Grant dateSep 11, 2001
Priority date
Expiry dateNov 13, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2039/522
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A highly conserved, immunologically accessible antigen at the surface of Neisseria meningitidis organisms. Immunotherapeutic, prophylactic and diagnostic compositions and methods useful in the treatment, prevention an diagnosis of Neisseria meningitidis diseases. A proteinase K resistant Neisseria meningitidis surface protein having an apparent molecular weight of 22 kDa, the corresponding nucleotide and derived amino acid sequences (SEQ ID NO: 1, NO:3, NO:5 and NO:7: SEQ ID NO: 2, NO:4, NO:6, and NO:8), recombinant DNA methods for the production of the Neisseria meningitidis 22 kDA surface protein, and antibodies that bind to the Neisseria meningitidis 22 kDA surface protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.