Biocompatible lubricious hydrophilic materials for medical devices

US6287707A · kind A · utility

Inventors

• Ajay Luthra · San Diego, US
• Shivpal S. Sandhu · Slough, GB

Key dates

• Filing date: Jun 26, 1998
• Grant date: Sep 11, 2001
• Expiry date: Jun 26, 2018

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/31935
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A biocompatible, lubricious, hydrophilic material useful for coating medical devices or for blending into polymer compositions intended for making medical devices comprises a terpolymer of 5 to 25 mole percent of a polymerisable monomer (1) having a polyethylene oxide unit with an average degree of polymerisation from 5 to 18 and a polymerisable carbon-carbon double bond, 5 to 30 mole percent of a polymerisable monomer (2) having a polyethylene oxide unit with an average degree of polymerisation from 19 to 65 and polymerisable carbon-carbon double bond, and 45 to 90 mole percent of an alkyl methacrylate (3): (1) CH.sub.2.dbd.C(R)--CO--[--O--CH.sub.2 --CH.sub.2 --].sub.n1 --O--R where n1 is from 5 to 18, and each R is independently H or CH.sub.3 ; (2) CH.sub.2.dbd.C(R)--CO--[--O--CH.sub.2 --CH.sub.2 --].sub.n2 --O--R where n2 is from 19 to 65 and each R is independently H or CH.sub.3 ; (3) CH.sub.2.dbd.C(CH.sub.3)--CO.sub.2 --(CH.sub.2).sub.m --CH.sub.3 where m is from 3 to 17, which may be made by the aqueous emulsion polymerisation of the monomers.