Antibiotic-based gene regulation system
US6287813A · kind A · utility
13Cited by
11References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 4, 1999 |
| Grant date | Sep 11, 2001 |
| Priority date | — |
| Expiry date | Oct 4, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/206
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a novel system for gene regulation in eukaryotic cells, and methods of using the same for protein production, tissue engineering and gene therapy. In particular, the invention provides a new system for antibiotic-regulated gene expression in eukaryotic cells based on sequences from Actinomycetes antibiotic resistance promoters, polypeptides that bind to the same in an antibiotic responsive manner, and nucleotides encoding such polypeptides. Further, the invention provides novel and sensitive methods of screening for candidate antibiotics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.