Characterization and use of an isolated uridine diphospho-glucuronosyltransferase
US6287834A · kind A · utility
3Cited by
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11Claims
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Key dates
| Filing date | Feb 8, 1999 |
| Grant date | Sep 11, 2001 |
| Priority date | — |
| Expiry date | Feb 8, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A uridine diphospho-glucuronosyltransferase (UGTB217) is provided. Methods of producing the enzyme and using the enzyme to identify potential compounds which inhibit or alter the activity of the enzyme are described. In addition, methods of using antibodies to localize the protein, or using the gene sequence or portions thereof for probes or using the gene sequence to produce expression-disrupting sense or antisense DNA fragments thereof, or antisense RNA, are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.