Acronycine derivatives, preparation method and pharmaceutical compositions
US6288073A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 19, 2000 |
| Grant date | Sep 11, 2001 |
| Priority date | — |
| Expiry date | Jun 19, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound selected from those of formula (I): ##STR1## in which: PA1 X and Y represent hydrogen, halogen, hydroxy, mercapto, cyano, nitro, alkyl, alkoxy, trihaloalkyl, optionally substituted amino, methylenedioxy, or ethylenedioxy, PA1 R.sub.1 represents hydrogen, or alkyl, PA1 R.sub.2 represents hydrogen, hydroxy, alkyl, alkoxy, alkylcarbonyloxy, or optionally substituted ammo, PA1 R.sub.3 and R.sub.4 represent hydrogen, or alkyl, PA1 A represents --CH.dbd.CH--, or --CH(R.sub.5)--CH(R.sub.6)-- wherein R.sub.5 and R.sub.6 are as defined in the description, their isomers, N-oxides, and pharmaceutically-acceptable acid or base addition salts thereof, and medicinal products containing the same which are useful in the treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.