Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolone carboxylic acid and naphthyridone carboxylic acid derivatives for treating Helicobacter pylori infections and the gastroduodenal diseases associated therewith

US6288081A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Uwe Petersen · Leverkusen, DE
• Michael Matzke · Wuppertal, DE
• Thomas Jaetsch · Cologne, DE
• Thomas Schenke · Odenthal, DE
• Thomas Himmler · Odenthal, DE
• Stephan Bartel · Bensberg, DE
• Bernd Baasner · Bensberg, DE
• Hans-Otto Werling · Wuppertal, DE
• Klaus Schaller · Wuppertal, DE
• Harald Labischinski · Wuppertal, DE
• Rainer Endermann · Wuppertal, DE

Key dates

• Filing date: Aug 6, 1999
• Grant date: Sep 11, 2001
• Expiry date: Aug 6, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/6561
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to the use of quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in position 7 by a 1-aminomethyl-2-oxa-7-azabicyclo[3.3.0]oct-7-yl radical, and of their salts for the therapy of Helicobacter pylori infections and associated gastroduodenal disorders.