Oil-free glycerophospholipid formulations and method for the production thereof

US6288130A · kind A · utility

Assignee

• SKW Trostberg Aktiengesellschaft · DE

Inventors

• Jurgen Heidlas · Trostberg, DE
• Karl-Heinz Zirzow · Trostberg, DE
• Johann Wiesmuller · Garching bei München, DE
• Martin Ober · Cham, DE
• Franz Michlbauer · Kirchweidach, DE
• Jurgen Graefe · Trostberg, DE

Key dates

• Filing date: Sep 20, 1999
• Grant date: Sep 11, 2001
• Expiry date: Sep 20, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2800/52
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to oil-free glycerophospholipid formulations which contain a homogeneous mixture of glycerophospholipids and an anhydrous, liquid polyol compound such as glycerol in a molar ratio of 1:0.1 to 1. These formulations are produced, eg, by extracting a starting material consisting of an oil-containing glycerophospholipid (mixture) and the polyol component with a compressed hydrocarbon (mixture) in a rectifying column. The oil-free formulation can be obtained from the melt at the bottom of the column in the form of free-flowing powder, which is ideally suited for stabilising oil-in-water emulsions.