Methods of synthesis of halogen base-modified oligonucleotides and subsequent labeling with a metal-catalyzed reaction
US6288221A · kind A · utility
29Cited by
8References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 19, 1999 |
| Grant date | Sep 11, 2001 |
| Priority date | — |
| Expiry date | Aug 19, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides metal-containing purines, pyrimidines, nucleosides, nucleotides and oligonucleotides; including phosphoramidite and photolabile derivatives thereof, including methods of making and method of using same. The present invention provides a method for detection of nucleic acid sequences via electrochemical or photochemical means.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.