Patent · US Expired

Preparation of biodegradable, biocompatible microparticles containing a biologically active agent

US6290983A · kind A · utility

16Cited by
22References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 26, 2000
Grant dateSep 18, 2001
Priority date
Expiry dateMay 26, 2020

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T428/2985
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method for preparing biodegradable, biocompatible microparticles. A first phase is prepared that includes a biodegradable, biocompatible polymer, an active agent, and a solvent. A second phase is prepared. The first and second phases are combined to form an emulsion in which the first phase is discontinuous and the second phase is continuous. The discontinuous first phase is separated from the continuous second phase. The residual level of solvent in the discontinuous first phase is reduced to less than about 2% by weight.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.