Mixed liposome pharmaceutical formulation with amphiphiles and phospholipids
US6290987A · kind A · utility
25Cited by
21References
34Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 7, 1999 |
| Grant date | Sep 18, 2001 |
| Priority date | — |
| Expiry date | Sep 7, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1272
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A mixed liposome pharmaceutical formulation with multilamellar vesicles is provided. The formulation comprises a pharmaceutical agent, water, an alkali metal alkyl sulfate, at least one membrane mimetic amphiphile, and at least one phospholipid. When aerosol delivery is intended, the formulation also comprises a propellant and a phenol. A metered dose dispenser containing the formulation, as well as a method of administering the formulation, are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.