Patent · US Expired

Methods, software and apparati for identifying genomic regions harboring a gene associated with a detectable trait

US6291182A · kind A · utility

43Cited by
1References
46Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 10, 1999
Grant dateSep 18, 2001
Priority date
Expiry dateNov 10, 2019

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG16B40/00
  • WIPO fieldComputer technology
  • WIPO sectorElectrical engineering

Abstract

The present invention relates to methods, software, and apparati for determining whether a genomic region harbors a gene associated with a detectable trait. In one embodiment, the present invention relates to a method of confirming that a genomic region harbors a gene associated with a detectable trait comprising the steps of identifying a candidate genomic region suspected of harboring the gene associated with the detectable trait, constructing a trait-associated distribution of association values using the biallelic markers in the candidate genomic region, identifying a plurality of biallelic markers in random genomic regions which are not suspected of harboring the gene associated with the detectable trait, constructing a random distribution of association values using the biallelic markers in the random genomic regions, comparing the trait-associated distribution of association values to the random distribution of association values, and determining whether the trait-associated distribution of association values and the random distribution of association values are significantly different from one another. In other embodiments, the present invention comprises software for perfo…

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