Methods for diagnosing atherosclerosis by measuring endogenous heparin and methods for treating atherosclerosis using heparin
US6291439A · kind A · utility
21Cited by
11References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 2, 1998 |
| Grant date | Sep 18, 2001 |
| Priority date | — |
| Expiry date | Sep 2, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods for measuring endogenous heparin in a mammal at levels that were previously undetectable. The present invention further features methods for assessing the risk for and assessing the progression of atherosclerosis and methods for treating or inhibiting the progression of atherosclerosis. The invention also features methods for monitoring plasma heparin levels in subjects undergoing heparin treatment. Additionally, the present invention provides kits for assaying for heparin in biological samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.