Tetrahydroquinolines, processes for their preparation, pharmaceutical compositions containing them, and their use to prevent or treat hyperlipoproteinaemia

US6291477A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Gunter Schmidt · Houghton, US
• Jurgen Stoltefuss · Haan, DE
• Michael Logers · Wuppertal, DE
• Arndt Brandes · Wuppertal, DE
• Carsten Schmeck · Wuppertal, DE
• Klaus-Dieter Bremm · Recklinghausen, DE
• Hilmar Bischoff · Wuppertal, DE
• Delf Schmidt · Wuppertal, DE

Key dates

• Filing date: Mar 10, 2000
• Grant date: Sep 18, 2001
• Expiry date: Mar 10, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The tetrahydroquinolines can be prepared by condensing appropriately substituted tetrahydroquinoline aldehydes with suitable substances and subsequently varying the substituents present by customary methods. The tetrahydroquinolines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of arteriosclerosis and dyslipidaemias.