Patent · US Expired

Mono- or polyenic carboxylic acid derivatives

US6291508A · kind A · utility

0Cited by
13References
8Claims
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Assignee

Inventors

Key dates

Filing dateSep 23, 1999
Grant dateSep 18, 2001
Priority date
Expiry dateSep 23, 2019

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Mono- or polyenic carboxylic acid derived compounds of the formula (1-I) or a physiologically acceptable salt thereof: EQU Z--(CR.sup.3.dbd.CR.sup.2).sub.n --COOR.sup.1 (1-I) wherein R.sup.1 is hydrogen or a carboxyl-protecting group; R.sup.2 and R.sup.3 are each independently hydrogen, halogen, linear lower alkyl, branched lower alkyl linear lower alkoxy, branched lower alkoxy or aryl, m is 1 to 3 and Z is a group ##STR1## or their salts have the potent ability to bind to retinoic acid receptors thus useful in treating psoriasis and rheumatoid arthritis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.