N-arloxyethyl-alkylamines for the treatment of depression
US6291683A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 13, 2000 |
| Grant date | Sep 18, 2001 |
| Priority date | — |
| Expiry date | Jun 13, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds useful for alleviating symptoms of depression are provided which have the following formula: ##STR1## wherein: PA1 R.sub.1 is hydrogen, lower alkyl or aryl; PA1 R.sub.2 is hydrogen, lower alkyl, phenyl or substituted phenyl; PA1 X and Y are each, independently, hydrogen, lower alkyl, lower alkoxy, or halogen, or together combine with the carbon atoms to which they are attached to complete a cyclopentyl, cyclohexyl, phenyl, pyrrolyl, pyranyl, pyridinyl, dihydrofuranyl, furanyl, dioxanyl, oxazolyl or isoxazolyl group; PA1 Z is hydrogen, halogen or lower alkoxy; with the proviso that when X, Y or Z represent lower alkoxy, they are not present at the ortho position; PA1 W is hydrogen, halogen, lower alkyl, cyano or a trifluoromethyl group; and PA1 n is 2-5; or pharmaceutically acceptable salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.