Polymers containing guanidinium groups as bile acid sequestrants
US6294163A · kind A · utility
49Cited by
27References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 2, 1998 |
| Grant date | Sep 25, 2001 |
| Priority date | — |
| Expiry date | Oct 2, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G73/0627
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises administering a therapeutically effective amount of a guanidinium moiety-containing polymer composition to a mammal, such as a human, whereby bile acids are sequestered. The polymers of the invention comprise guanidinium moieties and optionally, additional substituents such as a hydrophobic group, a quaternary ammonium-containing group or a combination thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.