Staphylococcus aureus antigen-containing whole cell vaccine
US6294177A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | May 10, 1999 |
| Grant date | Sep 25, 2001 |
| Priority date | — |
| Expiry date | May 10, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/6037
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A negatively-charged S. aureus antigen contains .beta.-hexosamine as a major carbohydrate component. S. aureus strains that carry the antigen account for nearly all of the clinically significant strains of S. aureus that are not Type 5 or Type 8 strains. The antigen can be used in combination with S. aureus Type 5 polysaccharide antigen and S. aureus Type 8 polysaccharide antigen to provide nearly 100% coverage of S. aureus infection. The antigen and antibodies to the antigen are useful in kits and assays for diagnosing S. aureus infection. A whole cell vaccine of cells that contain the antigen is particularly useful in the treatment of mastitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.