Replication genes and gene products from small cryptic plasmids and methods for constructing controlled-replication plasmid vectors
US6294372A · kind A · utility
4Cited by
1References
11Claims
0Family size
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Key dates
| Filing date | Mar 13, 1998 |
| Grant date | Sep 25, 2001 |
| Priority date | — |
| Expiry date | Mar 13, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The replication genes of small cryptic plasmids are isolated and used to construct controlled-replication plasmid vectors with the wide range of copy numbers controlled by defined helper plasmids. Controlled-replication vectors (RAMP vectors) can reach very high level of plasmid replication, which is not lethal to host unlike runaway replication vectors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.