Patent · US Expired

Oxindolylquinazoline derivatives as angiogenesis inhibitors

US6294532A · kind A · utility

61Cited by
32References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 3, 2000
Grant dateSep 25, 2001
Priority date
Expiry dateMay 3, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to compounds of formula (I) ##STR1## and salts thereof as further defined herein, wherein ring Z is a 6-membered heterocyclic ring containing 1 to 3 nitrogen atoms, and the use of such compounds and salts to inhibit the effects of VEGF and FGF, and in the treatment of a number of disease states including cancer and rheumatoid arthritis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.