Crystalline N-acetyl neuraminic acid derivatives and process for their preparation
US6294572A · kind A · utility
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32Claims
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Key dates
| Filing date | Jul 2, 1999 |
| Grant date | Sep 25, 2001 |
| Priority date | — |
| Expiry date | Jul 2, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Two useful crystal hydrates of 5-acetamido-2,3,4,5-tetradeoxy-4-guanidino-D-glycero-D-galacto-non-2-enopy ranosonic acid have either a low or high aspect ratio. These crystalline N-acetyl neurominic acid derivatives are favored for pharmaceutical formulation because of their physical properties. For example, the low aspect ratio crystal has good flow properties, and the high aspect ratio crystal has a stable water content over time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.