Process for the production of N-acylamino acids

US6294681A · kind A · utility

Assignee

• Degussa-Huels AG · DE

Inventors

• Karlheinz Drauz · Alzenau, DE
• Olaf Burkhardt · Kalmthout, BE
• Matthias Beller · Ostseebad Nienhagen, DE
• Markus Eckert · Bad Mergentheim, DE
• Wahed Ahmed Moradi · Monheim, DE
• Helfried Neumann · Rostock, DE

Key dates

• Filing date: Jun 26, 2000
• Grant date: Sep 25, 2001
• Expiry date: Jun 26, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides a process for producing N-acyl-protected amino acids with the general formula I ##STR1## by amidocarbonylation whereby carbon monoxide, an amide/nitrile and an aldehyde, are reacted in the presence of a metal catalysts such as rhodium, iridium or ruthenium catalysts.