Live attenuated Venezuelan Equire encephalitis vaccine

US6296854A · kind A · utility

Assignee

• The United States of America as represented by the Secretary of the Army · US

Inventors

• Peter Pushko · Frederick, US
• Michael Parker · Frederick, US
• Jonathan F. Smith · Cary, US
• Bruce Crise · Frederick, US

Key dates

• Filing date: Dec 7, 1999
• Grant date: Oct 2, 2001
• Expiry date: Dec 7, 2019

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S424/82
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A live attenuated Venezuelan equine encephalitis virus (VEE) is described which comprises a viral gene rearrangement. This rearranged attenuated virus is useful as vaccine for protection against infection with VEE. Methods of preparing the virus and methods of using the virus are described.