Recombinant cephalosporin C amidohydrolase in cephalosporin biosynthesis
US6297032A · kind A · utility
1Cited by
2References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 26, 1999 |
| Grant date | Oct 2, 2001 |
| Priority date | — |
| Expiry date | Jan 26, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/874
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to an enzyme process for the one-step conversion of cephalosporin C or a derivative thereof into 7-aminocephalosporanic acid or a corresponding derivative thereof. The one step conversion is effected using a cephalosphorin C amidohydrolase derived from Pseudomonas Vesicularis B965, or from any cephalosporin C amidolydrolase producing or potentially producing descendants thereof, or from expression of DNA derived from Pseudomonas Vesicularis B965 or any cephalosporin C amidohydrolase producing or potentially producing descendants thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.