Patent · US Expired

Antimicrobial cationic peptides

US6297215A · kind A · utility

18Cited by
17References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 7, 1999
Grant dateOct 2, 2001
Priority date
Expiry dateMay 7, 2019

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include NH.sub.2 -KWKSFIKKLTTAVKKVLTTGLPALIS-COOH (SEQ ID NO:1) and NH.sub.2 -KWKSFIKKLTSAAKKVVTTAKPLISS-COOH (SEQ ID NO:2). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. The peptides are particularly useful for inhibiting endotoxemia in a subject.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.