Uracil reductase inactivatores
US6297223A · kind A · utility
2Cited by
5References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 30, 2000 |
| Grant date | Oct 2, 2001 |
| Priority date | — |
| Expiry date | Jun 30, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Uracil reductase inactivators, notably a 5-substituted uracil or 5,6-dihydro-5-substituted uracil, potentiate 5-fluorouracil and find use particularly in the treatment of cancer. The 5-substituent is selected from bromo, iodo, cyano, halo-substituted C.sub.1-4 alkyl, C.sub.2-6 alkenyl, 1-halo-C.sub.2-6 alkenyl and halo-substituted C.sub.2-6 aklynyl.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.