Cyanoaziridines for treating cancer
US6297230A · kind A · utility
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2References
13Claims
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Assignee
Inventors
Key dates
| Filing date | Apr 10, 2000 |
| Grant date | Oct 2, 2001 |
| Priority date | — |
| Expiry date | Apr 10, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D203/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to novel anti-cancer compounds of the formula. ##STR1## wherein PA1 X is CN, PA1 R.sub.4 is hydrogen or lower alkyl; and PA1 R.sub.5 is lower alkyl, lower cycloalkyl, alkenyl, alkynyl, aryl, monosubstituted aryl, disubstituted aryl, aryl lower alkyl, lower alkoxycarbonyl lower alkyl, or heterocyclic ring, with the proviso that when X is CN, and R.sub.4 is hydrogen, then R.sub.5 is not CH.sub.3, C.sub.6 H.sub.5, or, p-nitrophenyl. PA1 R.sub.4, R.sub.5 and N taken together form a heterocyclic ring.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.