Telomere repeat binding factors and diagnostic and therapeutic use thereof
US6297356A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 4, 1998 |
| Grant date | Oct 2, 2001 |
| Priority date | — |
| Expiry date | Feb 4, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a novel nucleotide sequence encoding a telomeric protein which binds a repeat region of telomeric sequences, and to the protein encoded thereby. Also included within the invention are expression vectors for the production of the telomeric protein and host cells transformed with the nucleotide sequence. In addition, antibodies, probes and antagonists specific for the telomeric protein are contemplated. Methods of identifying antagonists of the telomeric protein, diagnostic methods of identifying the telomeric protein in a sample, and therapeutic uses of the telomeric protein, particularly in the treatment of aging and cancer, are also contemplated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.