Methods of immunization by administering fibrinogen binding protein or fragments thereof

US6299879A · kind A · utility

Assignee

• Alfa Laval Agri International Aktiebolag · SE

Inventors

• Maria K. Boden Wastfalt · Lund, SE
• Jan-Ingmar Flock · Bromma, SE

Key dates

• Filing date: Mar 25, 1999
• Grant date: Oct 9, 2001
• Expiry date: Mar 25, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K39/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides a method for immunizing a mammal against Staphylococcus infection comprising administering to that mammal a protein or fragment thereof comprising the amino acid sequence: (SEQ ID NO:8) SEGYGPREKK PVSINHNIVE YNDGTFKYQS RPKFNSTPKY IKFKHDYNIL EFNDGTFEYG ARPQFNKPAA KTDATIKKEQ KLIQAQNLVR EFEKTHTVSA HRKAQKAVNL VSFEYKVKKM VLQERIDNVL KQGLVR, or a fragment thereof retaining that portion of the sequence responsible for fibrinogen binding activity.