Hematopoietic stimulation
US6300314A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 3, 1999 |
| Grant date | Oct 9, 2001 |
| Priority date | — |
| Expiry date | May 3, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K35/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and products for stimulating hematopoiesis, preventing low levels of hematopoietic cells and producing increased numbers of hematopoietic and mature blood cells are provided. The methods and products can be used both in vivo and in vitro. The methods involve administering an agent of Formula I: ##STR1## wherein m is an integer between 0 and 10, inclusive; A and A.sub.1 are L-amino acid residues such that the A in each repeating bracketed unit can be the same or a different amino acid residue; the C bonded to B is in the L-configuration; the bonds between A and N, A.sub.1 and C, and between A.sub.1 and N are peptide bonds; and each X.sub.1 and X.sub.2 is, independently, a hydroxyl group or a group capable of being hydrolyzed to a hydroxyl group in aqueous solution at physiological pH. A particularly preferred agent that is useful in practicing the invention is a ValBoroPro.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.