Patent · US Expired

Azoles for treatment of fungal infections

US6300353A · kind A · utility

11Cited by
2References
37Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 5, 1999
Grant dateOct 9, 2001
Priority date
Expiry dateMar 5, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D249/08
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Azole derivatives of the formula I ##STR1## wherein PA1 R.sup.14, R.sup.15 are each independently hydrogen or fluorine, PA1 T is a group of the formula: ##STR2## wherein PA2 R.sup.9 is pyrrolidinyl or a group A--NH--B--, PA2 A is hydrogen or straight-chain or branched C.sub.1 -C.sub.5 alkyl; PA2 B is straight-chain or branched C.sub.1 -C.sub.4 alkylene, --CH.sub.2 --CONH--CH.sub.2 or --CH.sub.2 CH.sub.2 CH.sub.2 --CH(NH.sub.2); and PA2 X.sup.- is a pharmaceutically acceptable anion; and pharmaceutically acceptable salts of said compounds, and hydrates and solvates of the compounds of formula I and the salts thereof can be used in the production of medicaments for treating fungal infections and mycoses.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.