Selenoproteins, coding sequences and methods
US6303295A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 12, 1996 |
| Grant date | Oct 16, 2001 |
| Priority date | — |
| Expiry date | Jul 12, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16322
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides a method for the identification of nucleotide sequences which encode selenoproteins. Nucleotide sequences are translated in all potential reading frames, those with a relatively large number of UGA or TGA codons are noted, and frameshift-dependent open reading frames and SECIS elements are identified as associated with selenoprotein coding sequences, especially those within or overlapping known open reading frames. Further provided are selenoprotein coding sequences which are associated with certain viruses (e.g., HIV and Ebola), cancer-related genes and coding sequences related to normal functioning of the immune system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.