Cell based assay for identifying sh2-domain-specific signal transducer antagonist
US6303319A · kind A · utility
11Cited by
2References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 15, 1998 |
| Grant date | Oct 16, 2001 |
| Priority date | — |
| Expiry date | Jul 15, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/81
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods and compositions for identifying inhibitors of the interaction between phosphopeptide binding pairs, i.e., a protein domain having at least one phosphopeptide binding domain and the phosphorylated ligands that bind these domains. These inhibitors may be used for pharmaceutical compositions and in therapeutic treatments for diseases in which a phosphopeptide domain binding is implicated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.