Patent · US Expired

Rapid flow-through binding assay apparatus and method therefor

US6303389A · kind A · utility

66Cited by
14References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 29, 1998
Grant dateOct 16, 2001
Priority date
Expiry dateJun 29, 2018

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/25375
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The invention includes assay cassettes that can be employed during rapid flow-through binding assays. The assay cassettes can be disposable units suitable for one-time use and readily assembled to include a filter membrane carried between an upper plate and a lower plate. A pattern of channels can extend through the top plate to allow a fluid sample to be applied through the top plate and onto the filter. The bottom plate can include a plurality of channels that are aligned with the channel of the top plate and which will allow a negative pressure to be applied to the underside of the filter membrane to draw the sample through the filter. In one embodiment, the cassette includes a frangible section that allows the cassette to be divided into a first and second component.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.